Here's my Formation:
-----------------Stekelenburg
------De Jong------Heitinga-----Escude---
-------------------Galasek----------------
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Obodai-------------Sneijder---------Maxwell
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Rosales-----------Charisteas----------Mitea
The whole backline is solid, and Stekelenburg is amazing, he will take out most shots.
Galasek is my free-man, he runs pretty fast, and can take the ball from anyone. He moves on both sides, and the middle.
In the midfield I have two central-midfielders, Obodai and Maxwell, that run up both throught the middle and the wings, but their key job is to return fast and defend.
Both Rosales and Mitea are very fast, they usually play on the opponent's defence line, with Sneijder serving up long passes to them. They both actually work pretty well with the midfield Maxwell and Obodai, who have an excellent middle-shoot ability, I use the wing-forwards to make back-crosses to them alot.
Charisteas is great at finishing plays and midrange shooting, so he just stands there and receives crosses. He wins almost all aerial balls, and gives counters with precission.
Subs:
Rosenberg comes in when I need more control in the attack, he's not fast, bt he ca swirl between the lines.
Piennar is very good at passing, but his definition is bad, I usually sub him for either Obodai or Maxwell.
Linberg is pretty good, he's my sub for Sneijder.
Maduro comes in on the back line, he's a really good defender.